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Detecting G protein-coupled receptor complexes in postmortem human brain with proximity ligation assay and a Bayesian classifier

Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions between the dopamine D2 receptor (D2R) and the adenosine A2A receptor (A2AR). A2AR-D2R complexes have been detecte...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Mészáros, József, Walle, Roman, Fan, Rongxi, Sun, Ziyi, Dwork, Andrew J, Trifilieff, Pierre, Javitch, Jonathan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092707/
https://www.ncbi.nlm.nih.gov/pubmed/31859535
http://dx.doi.org/10.2144/btn-2019-0083