An in vivo cell-based assay for investigating the specific interaction between the SARS-CoV N-protein and its viral RNA packaging sequence

The SARS-CoV nucleocapsid (N) protein serves multiple functions in viral replication, transcription, and assembly of the viral genome complex. Coronaviruses specifically package genomic RNA into assembled virions, and in SARS-CoV, it is reported that this process is driven by an interaction between...

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Detalles Bibliográficos
Autores principales: Woo, Jiwon, Lee, Eunice Yoojin, Lee, Mirae, Kim, Taeyeon, Cho, Yong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092827/
https://www.ncbi.nlm.nih.gov/pubmed/31594639
http://dx.doi.org/10.1016/j.bbrc.2019.09.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092827/
https://www.ncbi.nlm.nih.gov/pubmed/31594639
http://dx.doi.org/10.1016/j.bbrc.2019.09.115

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