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An in vivo cell-based assay for investigating the specific interaction between the SARS-CoV N-protein and its viral RNA packaging sequence
The SARS-CoV nucleocapsid (N) protein serves multiple functions in viral replication, transcription, and assembly of the viral genome complex. Coronaviruses specifically package genomic RNA into assembled virions, and in SARS-CoV, it is reported that this process is driven by an interaction between...
Autores principales: | Woo, Jiwon, Lee, Eunice Yoojin, Lee, Mirae, Kim, Taeyeon, Cho, Yong-Eun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092827/ https://www.ncbi.nlm.nih.gov/pubmed/31594639 http://dx.doi.org/10.1016/j.bbrc.2019.09.115 |
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