Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines

Initial in vitro investigations demonstrated type I interferons (IFNs: IFN-α, IFN-β) to inhibit replication of SARS coronavirus (SARS-CoV), but found the nucleoside analogue ribavirin ineffective in Vero cells. In this report, ribavirin was shown to inhibit SARS-CoV replication in five different cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgenstern, Birgit, Michaelis, Martin, Baer, Patrick C., Doerr, Hans W., Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092851/
https://www.ncbi.nlm.nih.gov/pubmed/15607755
http://dx.doi.org/10.1016/j.bbrc.2004.11.128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092851/
https://www.ncbi.nlm.nih.gov/pubmed/15607755
http://dx.doi.org/10.1016/j.bbrc.2004.11.128

Ejemplares similares