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Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines
Initial in vitro investigations demonstrated type I interferons (IFNs: IFN-α, IFN-β) to inhibit replication of SARS coronavirus (SARS-CoV), but found the nucleoside analogue ribavirin ineffective in Vero cells. In this report, ribavirin was shown to inhibit SARS-CoV replication in five different cel...
Autores principales: | Morgenstern, Birgit, Michaelis, Martin, Baer, Patrick C., Doerr, Hans W., Cinatl, Jindrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092851/ https://www.ncbi.nlm.nih.gov/pubmed/15607755 http://dx.doi.org/10.1016/j.bbrc.2004.11.128 |
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