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Retardation of cell growth by avian reovirus p17 through the activation of p53 pathway

The second open reading frame of avian reovirus S1 gene segment encodes a 17 kDa non-structural protein, named p17. The biological role of p17 is fully unknown so far. Using trypan blue dye exclusion and MTT assay, we demonstrated that the ectopic expression of p17 results in the reduction of viable...

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Detalles Bibliográficos
Autores principales: Liu, Hung-Jen, Lin, Ping-Yuan, Lee, Jeng-Woei, Hsu, Hsue-Yin, Shih, Wen-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092890/
https://www.ncbi.nlm.nih.gov/pubmed/16143310
http://dx.doi.org/10.1016/j.bbrc.2005.08.149