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Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (CoV), a type I transmembrane envelope glycoprotein, consists of S1 and S2 domains responsible for virus binding and fusion, respectively. The S1 contains a receptor-binding domain (RBD) that can specifically bind to angio...

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Detalles Bibliográficos
Autores principales: He, Yuxian, Zhou, Yusen, Liu, Shuwen, Kou, Zhihua, Li, Wenhui, Farzan, Michael, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092904/
https://www.ncbi.nlm.nih.gov/pubmed/15474494
http://dx.doi.org/10.1016/j.bbrc.2004.09.106