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A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells

Small interfering RNAs (siRNAs) have become the most powerful and widely used gene silencing reagents for reverse functional genomics and molecular therapeutics. The key challenge for achieving effective gene silencing in particular for the purpose of the therapeutics is primarily dependent on the e...

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Detalles Bibliográficos
Autores principales: Hung, Chuan-Fu, Lu, Kuang-Chu, Cheng, Tsung-Lin, Wu, Ren-Huang, Huang, Lin-Ya, Teng, Chiao-Fang, Chang, Wen-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092908/
https://www.ncbi.nlm.nih.gov/pubmed/16793020
http://dx.doi.org/10.1016/j.bbrc.2006.05.164