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A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells
Small interfering RNAs (siRNAs) have become the most powerful and widely used gene silencing reagents for reverse functional genomics and molecular therapeutics. The key challenge for achieving effective gene silencing in particular for the purpose of the therapeutics is primarily dependent on the e...
Autores principales: | Hung, Chuan-Fu, Lu, Kuang-Chu, Cheng, Tsung-Lin, Wu, Ren-Huang, Huang, Lin-Ya, Teng, Chiao-Fang, Chang, Wen-Tsan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092908/ https://www.ncbi.nlm.nih.gov/pubmed/16793020 http://dx.doi.org/10.1016/j.bbrc.2006.05.164 |
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