The substrate specificity of SARS coronavirus 3C-like proteinase

The 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS) has been proposed to be a key target for structural based drug design against SARS. We have designed and synthesized 34 peptide substrates and determined their hydrolysis activities. The conserved core sequence of the nat...

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Detalles Bibliográficos
Autores principales: Fan, Keqiang, Ma, Liang, Han, Xiaofeng, Liang, Huanhuan, Wei, Ping, Liu, Ying, Lai, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092912/
https://www.ncbi.nlm.nih.gov/pubmed/15752746
http://dx.doi.org/10.1016/j.bbrc.2005.02.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092912/
https://www.ncbi.nlm.nih.gov/pubmed/15752746
http://dx.doi.org/10.1016/j.bbrc.2005.02.061

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