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The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase()
The 3C-like proteinase of severe acute respiratory syndrome (SARS) coronavirus has been proposed to be a key target for structural-based drug design against SARS. Accurate determination of the dimer dissociation constant and the role of the N-finger (residues 1–7) will provide more insights into the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092940/ https://www.ncbi.nlm.nih.gov/pubmed/16329994 http://dx.doi.org/10.1016/j.bbrc.2005.11.102 |