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TGEV nucleocapsid protein induces cell cycle arrest and apoptosis through activation of p53 signaling

Our previous studies showed that TGEV infection could induce cell cycle arrest and apoptosis via activation of p53 signaling in cultured host cells. However, it is unclear which viral gene causes these effects. In this study, we investigated the effects of TGEV nucleocapsid (N) protein on PK-15 cell...

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Detalles Bibliográficos
Autores principales: Ding, Li, Huang, Yong, Du, Qian, Dong, Feng, Zhao, Xiaomin, Zhang, Wenlong, Xu, Xingang, Tong, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092941/
https://www.ncbi.nlm.nih.gov/pubmed/24548406
http://dx.doi.org/10.1016/j.bbrc.2014.02.039