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Immunological, structural, and preliminary X-ray diffraction characterizations of the fusion core of the SARS-coronavirus spike protein()

The SARS-CoV spike protein, a glycoprotein essential for viral entry, is a primary target for vaccine and drug development. Two peptides denoted HR-N(SN50) and HR-C(SC40), corresponding to the Leu/Ile/Val-rich heptad-repeat regions from the N-terminal and C-terminal segments of the SARS-CoV spike S2...

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Detalles Bibliográficos
Autores principales: Hsu, Chun-Hua, Ko, Tzu-Ping, Yu, Hui-Ming, Tang, Tswen-Kei, Chen, Shui-Tsung, Wang, Andrew H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092949/
https://www.ncbi.nlm.nih.gov/pubmed/15474492
http://dx.doi.org/10.1016/j.bbrc.2004.09.116