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Immunological, structural, and preliminary X-ray diffraction characterizations of the fusion core of the SARS-coronavirus spike protein()
The SARS-CoV spike protein, a glycoprotein essential for viral entry, is a primary target for vaccine and drug development. Two peptides denoted HR-N(SN50) and HR-C(SC40), corresponding to the Leu/Ile/Val-rich heptad-repeat regions from the N-terminal and C-terminal segments of the SARS-CoV spike S2...
Autores principales: | Hsu, Chun-Hua, Ko, Tzu-Ping, Yu, Hui-Ming, Tang, Tswen-Kei, Chen, Shui-Tsung, Wang, Andrew H.-J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092949/ https://www.ncbi.nlm.nih.gov/pubmed/15474492 http://dx.doi.org/10.1016/j.bbrc.2004.09.116 |
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