MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex

IFNβ innate immune plays an essential role in antiviral immune. Previous reports suggested that many important regulatory proteins in innate immune pathway may be modified by ubiquitin and that many de-ubiquitination (DUB) proteins may affect immunity. Monocyte chemotactic protein-inducing protein 1...

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Detalles Bibliográficos
Autores principales: Chen, Xiaojuan, Zhao, Qian, Xie, Qing, Xing, Yaling, Chen, Zhongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092953/
https://www.ncbi.nlm.nih.gov/pubmed/29920243
http://dx.doi.org/10.1016/j.bbrc.2018.06.083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092953/
https://www.ncbi.nlm.nih.gov/pubmed/29920243
http://dx.doi.org/10.1016/j.bbrc.2018.06.083

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