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MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex
IFNβ innate immune plays an essential role in antiviral immune. Previous reports suggested that many important regulatory proteins in innate immune pathway may be modified by ubiquitin and that many de-ubiquitination (DUB) proteins may affect immunity. Monocyte chemotactic protein-inducing protein 1...
Autores principales: | Chen, Xiaojuan, Zhao, Qian, Xie, Qing, Xing, Yaling, Chen, Zhongbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092953/ https://www.ncbi.nlm.nih.gov/pubmed/29920243 http://dx.doi.org/10.1016/j.bbrc.2018.06.083 |
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