Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons

Pathological accumulation of microtubule associated protein tau in neurons is a major neuropathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Several attempts have been made to promote clearance of pathological tau (p-Tau) from neurons. Transcription factor EB (TFEB) has show...

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Detalles Bibliográficos
Autores principales: Binder, Jessica L., Chander, Praveen, Deretic, Vojo, Weick, Jason P., Bhaskar, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092971/
https://www.ncbi.nlm.nih.gov/pubmed/32208437
http://dx.doi.org/10.1371/journal.pone.0230026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092971/
https://www.ncbi.nlm.nih.gov/pubmed/32208437
http://dx.doi.org/10.1371/journal.pone.0230026

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