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Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons
Pathological accumulation of microtubule associated protein tau in neurons is a major neuropathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Several attempts have been made to promote clearance of pathological tau (p-Tau) from neurons. Transcription factor EB (TFEB) has show...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092971/ https://www.ncbi.nlm.nih.gov/pubmed/32208437 http://dx.doi.org/10.1371/journal.pone.0230026 |