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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes
The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibility loci in mouse and human. eIF5A is the only protein known to contain hypusine (hydroxyputrescine lysine), a polyamine-derived amino acid formed post-translationally in a reaction catalyzed by deoxyhypusine s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092972/ https://www.ncbi.nlm.nih.gov/pubmed/32208453 http://dx.doi.org/10.1371/journal.pone.0230627 |