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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes

The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibility loci in mouse and human. eIF5A is the only protein known to contain hypusine (hydroxyputrescine lysine), a polyamine-derived amino acid formed post-translationally in a reaction catalyzed by deoxyhypusine s...

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Detalles Bibliográficos
Autores principales:	Mastracci, Teresa L., Colvin, Stephanie C., Padgett, Leah R., Mirmira, Raghavendra G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092972/ https://www.ncbi.nlm.nih.gov/pubmed/32208453 http://dx.doi.org/10.1371/journal.pone.0230627

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