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Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells

Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug,...

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Detalles Bibliográficos
Autores principales: López-Contreras, Freddy, Muñoz-Uribe, Matías, Pérez-Laines, Jorge, Ascencio-Leal, Laura, Rivera-Dictter, Andrés, Martin-Martin, Antonia, Burgos, Rafael A., Alarcon, Pablo, López-Muñoz, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093016/
https://www.ncbi.nlm.nih.gov/pubmed/32256343
http://dx.doi.org/10.3389/fphar.2019.01670