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Engagement of monocytes, NK cells, and CD4(+) Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIV(mac251) vaginal acquisition

The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vaccine regimen decreased the risk of virus acquisition in Indian...

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Detalles Bibliográficos
Autores principales: Gorini, Giacomo, Fourati, Slim, Vaccari, Monica, Rahman, Mohammad Arif, Gordon, Shari N., Brown, Dallas R., Law, Lynn, Chang, Jean, Green, Richard, Barrenäs, Fredrik, Liyanage, Namal P. M., Doster, Melvin N., Schifanella, Luca, Bissa, Massimiliano, Silva de Castro, Isabela, Washington-Parks, Robyn, Galli, Veronica, Fuller, Deborah H., Santra, Sampa, Agy, Michael, Pal, Ranajit, Palermo, Robert E., Tomaras, Georgia D., Shen, Xiaoying, LaBranche, Celia C., Montefiori, David C., Venzon, David J., Trinh, Hung V., Rao, Mangala, Gale, Michael, Sekaly, Rafick P., Franchini, Genoveffa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093029/
https://www.ncbi.nlm.nih.gov/pubmed/32163525
http://dx.doi.org/10.1371/journal.ppat.1008377