Cargando…
Comprehensive analysis of structural and sequencing data reveals almost unconstrained chain pairing in TCRαβ complex
Antigen recognition by T-cells is guided by the T-cell receptor (TCR) heterodimer formed by α and β chains. A huge diversity of TCR sequences should be maintained by the immune system in order to be able to mount an effective response towards foreign pathogens, so, due to cooperative binding of α an...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093030/ https://www.ncbi.nlm.nih.gov/pubmed/32163410 http://dx.doi.org/10.1371/journal.pcbi.1007714 |