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Expanding the CRISPR Toolbox in Culicine Mosquitoes: In Vitro Validation of Pol III Promoters

[Image: see text] CRISPR–Cas9-based “gene drive” technologies have been proposed as a novel and effective means of controlling human diseases vectored by mosquitoes. However, more complex designs than those demonstrated to date—and an expanded molecular toolbox with which to build them—will be requi...

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Detalles Bibliográficos
Autores principales: Anderson, Michelle A. E., Purcell, Jessica, Verkuijl, Sebald A. N., Norman, Victoria C., Leftwich, Philip T., Harvey-Samuel, Tim, Alphey, Luke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093051/
https://www.ncbi.nlm.nih.gov/pubmed/32129976
http://dx.doi.org/10.1021/acssynbio.9b00436