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Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (early- to late-bud) and studied its role during tis...

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Detalles Bibliográficos
Autores principales: Sousounis, Konstantinos, Bryant, Donald M, Martinez Fernandez, Jose, Eddy, Samuel S, Tsai, Stephanie L, Gundberg, Gregory C, Han, Jihee, Courtemanche, Katharine, Levin, Michael, Whited, Jessica L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093111/
https://www.ncbi.nlm.nih.gov/pubmed/32142407
http://dx.doi.org/10.7554/eLife.51217