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Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration
How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (early- to late-bud) and studied its role during tis...
Autores principales: | Sousounis, Konstantinos, Bryant, Donald M, Martinez Fernandez, Jose, Eddy, Samuel S, Tsai, Stephanie L, Gundberg, Gregory C, Han, Jihee, Courtemanche, Katharine, Levin, Michael, Whited, Jessica L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093111/ https://www.ncbi.nlm.nih.gov/pubmed/32142407 http://dx.doi.org/10.7554/eLife.51217 |
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