An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones

Adult Drosophila Malpighian tubules have low rates of cell turnover but are vulnerable to damage caused by stones, like their mammalian counterparts, kidneys. We show that Drosophilarenal stem cells (RSCs) in the ureter and lower tubules comprise a unique, unipotent regenerative compartment. RSCs re...

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Detalles Bibliográficos
Autores principales: Wang, Chenhui, Spradling, Allan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093152/
https://www.ncbi.nlm.nih.gov/pubmed/32175841
http://dx.doi.org/10.7554/eLife.54096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093152/
https://www.ncbi.nlm.nih.gov/pubmed/32175841
http://dx.doi.org/10.7554/eLife.54096

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