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Survey of senescent cell markers with age in human tissues

Cellular senescence, triggered by sublethal damage, is characterized by indefinite growth arrest, altered gene expression patterns, and a senescence-associated secretory phenotype. While the accumulation of senescent cells during aging decreases tissue function and promotes many age-related diseases...

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Detalles Bibliográficos
Autores principales: Idda, M. Laura, McClusky, Waverly G., Lodde, Valeria, Munk, Rachel, Abdelmohsen, Kotb, Rossi, Martina, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093180/
https://www.ncbi.nlm.nih.gov/pubmed/32160592
http://dx.doi.org/10.18632/aging.102903