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Exosomal miR-19a from adipose-derived stem cells suppresses differentiation of corneal keratocytes into myofibroblasts

In this study, we investigated the effects of exosomal microRNAs (miRNAs) from adipose-derived stem cells (ADSCs) on the differentiation of rabbit corneal keratocytes. Keratocytes grown in 10% FBS differentiated into myofibroblasts by increasing HIPK2 kinase levels and activity. HIPK2 enhanced p53 a...

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Detalles Bibliográficos
Autores principales: Shen, Ting, Zheng, Qingqing, Luo, Hongbo, Li, Xin, Chen, Zhuo, Song, Zeyu, Zhou, Guanfang, Hong, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093196/
https://www.ncbi.nlm.nih.gov/pubmed/32112551
http://dx.doi.org/10.18632/aging.102802