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Irisin activates Opa1-induced mitophagy to protect cardiomyocytes against apoptosis following myocardial infarction
Myocardial infarction is characterized by sudden ischemia and cardiomyocyte death. Mitochondria have critical roles in regulating cardiomyocyte viability and can sustain damage under ischemic conditions. Mitophagy is a mechanism by which damaged mitochondria are removed by autophagy to maintain mito...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093202/ https://www.ncbi.nlm.nih.gov/pubmed/32155590 http://dx.doi.org/10.18632/aging.102899 |