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Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies
BACKGROUND: BRIP1 is a helicase that partners with BRCA1 in the homologous recombination (HR) step in the repair of DNA inter-strand cross-link lesions. It is a rare cause of hereditary ovarian cancer in patients with no mutations of BRCA1 or BRCA2. The role of the protein in other cancers such as g...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Baishideng Publishing Group Inc
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093310/ https://www.ncbi.nlm.nih.gov/pubmed/32231423 http://dx.doi.org/10.3748/wjg.v26.i11.1197 |