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A Benziodoxole-Based Hypervalent Iodine(III) Compound Functioning as a Peptide Coupling Reagent

1-Benzoyloxy-1,2-benziodoxol-3-(1H)-one (IBA-OBz), a readily available and bench stable benziodoxole-based iodine(III) reagent, can be employed for the synthesis of dipeptides from various standard and sterically hindered amino acids in the presence of (4-MeOC(6)H(4))(3)P. The combined system of IBA...

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Detalles Bibliográficos
Autores principales: Qiu, Li-Jun, Liu, Dan, Zheng, Ke, Zhang, Ming-Tao, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093377/
https://www.ncbi.nlm.nih.gov/pubmed/32258000
http://dx.doi.org/10.3389/fchem.2020.00183