Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality

Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms and microRNA (miRNA) processing, rendering ADAR1 essential for life. Methods and...

Descripción completa

Detalles Bibliográficos
Autores principales: el Azzouzi, Hamid, Vilaça, Andreia P., Feyen, Dries A. M., Gommans, Willemijn M., de Weger, Roel A., Doevendans, Pieter A. F., Sluijter, Joost P. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093378/
https://www.ncbi.nlm.nih.gov/pubmed/32258062
http://dx.doi.org/10.3389/fcvm.2020.00030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093378/
https://www.ncbi.nlm.nih.gov/pubmed/32258062
http://dx.doi.org/10.3389/fcvm.2020.00030

Ejemplares similares