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Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality

Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms and microRNA (miRNA) processing, rendering ADAR1 essential for life. Methods and...

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Detalles Bibliográficos
Autores principales:	el Azzouzi, Hamid, Vilaça, Andreia P., Feyen, Dries A. M., Gommans, Willemijn M., de Weger, Roel A., Doevendans, Pieter A. F., Sluijter, Joost P. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093378/ https://www.ncbi.nlm.nih.gov/pubmed/32258062 http://dx.doi.org/10.3389/fcvm.2020.00030

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