Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

Aging is characterized by a gradual loss of function occurring at the molecular, cellular, tissue and organismal levels. At the chromatin level, aging associates with progressive accumulation of epigenetic errors that eventually lead to aberrant gene regulation, stem cell exhaustion, senescence, and...

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Detalles Bibliográficos
Autores principales: Sarkar, Tapash Jay, Quarta, Marco, Mukherjee, Shravani, Colville, Alex, Paine, Patrick, Doan, Linda, Tran, Christopher M., Chu, Constance R., Horvath, Steve, Qi, Lei S., Bhutani, Nidhi, Rando, Thomas A., Sebastiano, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093390/
https://www.ncbi.nlm.nih.gov/pubmed/32210226
http://dx.doi.org/10.1038/s41467-020-15174-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093390/
https://www.ncbi.nlm.nih.gov/pubmed/32210226
http://dx.doi.org/10.1038/s41467-020-15174-3

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