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Time-resolved fluorescence microscopy with phasor analysis for visualizing multicomponent topical drug distribution within human skin

Understanding a drug candidate’s pharmacokinetic (PK) parameters is a challenging but essential aspect of drug development. Investigating the penetration and distribution of a topical drug’s active pharmaceutical ingredient (API) allows for evaluating drug delivery and efficacy, which is necessary t...

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Detalles Bibliográficos
Autores principales: Jeong, Sinyoung, Greenfield, Daniel A., Hermsmeier, Maiko, Yamamoto, Akira, Chen, Xin, Chan, Kin F., Evans, Conor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093415/
https://www.ncbi.nlm.nih.gov/pubmed/32210332
http://dx.doi.org/10.1038/s41598-020-62406-z