Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α(1)β(2)γ(2L) GABA(A) receptor and spontaneous neuronal network function in vitro

Concerns about the neurotoxic potential of polyfluoroalkyl substances (PFAS) such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) increase, although their neurotoxic mechanisms of action remain debated. Considering the importance of the GABA(A) receptor in neuronal function, we...

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Detalles Bibliográficos
Autores principales: Tukker, Anke M., Bouwman, Lianne M. S., van Kleef, Regina G. D. M., Hendriks, Hester S., Legler, Juliette, Westerink, Remco H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093421/
https://www.ncbi.nlm.nih.gov/pubmed/32210279
http://dx.doi.org/10.1038/s41598-020-62152-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093421/
https://www.ncbi.nlm.nih.gov/pubmed/32210279
http://dx.doi.org/10.1038/s41598-020-62152-2

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