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Antibody epitope repertoire analysis enables rapid antigen discovery and multiplex serology

The detection of pathogen-specific antibodies remains a cornerstone of clinical diagnostics. Yet, many test exhibit undesirable performance or are completely lacking. Given this, we developed serum epitope repertoire analysis (SERA), a method to rapidly discover conserved, pathogen-specific antigens...

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Detalles Bibliográficos
Autores principales: Kamath, Kathy, Reifert, Jack, Johnston, Timothy, Gable, Cameron, Pantazes, Robert J., Rivera, Hilda N., McAuliffe, Isabel, Handali, Sukwan, Daugherty, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093460/
https://www.ncbi.nlm.nih.gov/pubmed/32210339
http://dx.doi.org/10.1038/s41598-020-62256-9