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Dimensionality reduction by UMAP to visualize physical and genetic interactions

Dimensionality reduction is often used to visualize complex expression profiling data. Here, we use the Uniform Manifold Approximation and Projection (UMAP) method on published transcript profiles of 1484 single gene deletions of Saccharomyces cerevisiae. Proximity in low-dimensional UMAP space iden...

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Detalles Bibliográficos
Autores principales: Dorrity, Michael W., Saunders, Lauren M., Queitsch, Christine, Fields, Stanley, Trapnell, Cole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093466/
https://www.ncbi.nlm.nih.gov/pubmed/32210240
http://dx.doi.org/10.1038/s41467-020-15351-4