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miR-216a-targeting theranostic nanoparticles promote proliferation of insulin-secreting cells in type 1 diabetes animal model

Aberrant expression of miRNAs in pancreatic islets is closely related to the development of type 1 diabetes (T1D). The aim of this study was to identify key miRNAs dysregulated in pancreatic islets during T1D progression and to develop a theranostic approach to modify their expression using an MRI-b...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Liu, Qiong, Zhao, Hongwei, Bishop, Jack Owen, Zhou, Guoli, Olson, L. Karl, Moore, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093482/
https://www.ncbi.nlm.nih.gov/pubmed/32210316
http://dx.doi.org/10.1038/s41598-020-62269-4