Sperm SPACA6 protein is required for mammalian Sperm-Egg Adhesion/Fusion

Three genes are known to be essential for gamete adhesion/fusion (Cd9, Izumo1 and Juno). Here, we confirmed that Spaca6 null males are infertile and showed that their sperm accumulate in the perivitelline space but are unable to fuse with oocyte. Like IZUMO1, SPACA6 which is expressed by human sperm...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbaux, Sandrine, Ialy-Radio, Côme, Chalbi, Myriam, Dybal, Elisa, Homps-Legrand, Méline, Do Cruzeiro, Marcio, Vaiman, Daniel, Wolf, Jean-Philippe, Ziyyat, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093486/
https://www.ncbi.nlm.nih.gov/pubmed/32210282
http://dx.doi.org/10.1038/s41598-020-62091-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093486/
https://www.ncbi.nlm.nih.gov/pubmed/32210282
http://dx.doi.org/10.1038/s41598-020-62091-y

Ejemplares similares