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In-depth characterization of a novel live-attenuated Mayaro virus vaccine candidate using an immunocompetent mouse model of Mayaro disease

Mayaro virus (MAYV) is endemic in South American countries where it is responsible for sporadic outbreaks of acute febrile illness. The hallmark of MAYV infection is a highly debilitating and chronic arthralgia. Although MAYV emergence is a potential threat, there are no specific therapies or licens...

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Detalles Bibliográficos
Autores principales: Mota, Mânlio Tasso de Oliveira, Costa, Vivian Vasconcelos, Sugimoto, Michelle Amantéa, Guimarães, Georgia de Freitas, Queiroz-Junior, Celso Martins, Moreira, Thaiane Pinto, de Sousa, Carla Daiane, Santos, Franciele Martins, Queiroz, Victoria Fulgêncio, Passos, Ingredy, Hubner, Josy, Souza, Danielle Gloria, Weaver, Scott C., Teixeira, Mauro Martins, Nogueira, Maurício Lacerda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093544/
https://www.ncbi.nlm.nih.gov/pubmed/32210270
http://dx.doi.org/10.1038/s41598-020-62084-x