Isorhynchophylline Exerts Antinociceptive Effects on Behavioral Hyperalgesia and Allodynia in a Mouse Model of Neuropathic Pain: Evidence of a 5-HT(1A) Receptor-Mediated Mechanism

Chronic neuropathic pain poses a significant health problem, for which effective therapy is lacking. The current work aimed to investigate the potential antinociceptive efficacy of isorhynchophylline, an oxindole alkaloid, against neuropathic pain and elucidate mechanisms. Male C57BL/6J mice were su...

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Detalles Bibliográficos
Autores principales: Gao, Ke-Xin, Zhao, Qing, Wang, Gang-Ren, Yu, Lu, Wu, Jia-Yi, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093567/
https://www.ncbi.nlm.nih.gov/pubmed/32256369
http://dx.doi.org/10.3389/fphar.2020.00318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093567/
https://www.ncbi.nlm.nih.gov/pubmed/32256369
http://dx.doi.org/10.3389/fphar.2020.00318

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