Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival

Significance: Glioblastoma multiforme (GBM) is the most frequently diagnosed adult primary brain malignancy with poor patient prognosis. GBM can recur despite aggressive treatment due to therapeutically resistant glioblastoma stem cells (GSCs) that may exhibit metabolic plasticity. Aim: Intrinsic ni...

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Detalles Bibliográficos
Autores principales: Schroeder, Alexandra B., Pointer, Kelli B., Clark, Paul A., Datta, Rupsa, Kuo, John S., Eliceiri, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Microscopy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093735/
https://www.ncbi.nlm.nih.gov/pubmed/32216192
http://dx.doi.org/10.1117/1.JBO.25.3.036502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093735/
https://www.ncbi.nlm.nih.gov/pubmed/32216192
http://dx.doi.org/10.1117/1.JBO.25.3.036502

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