Renin Promotes STAT4 Phosphorylation to Induce IL-17 Production in Keratinocytes of Oral Lichen Planus

Interleukin-17 (IL-17) is highly expressed in the epithelial layer of oral lichen planus (OLP), but the underlying mechanism for IL-17 overexpression remains unknown. Here, we identify renin that is induced by NF-κB pathway contributes to the increase of IL-17 in human oral keratinocytes (HOKs). We...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Xuejun, Xie, Hanting, Nguyen, Tivoli, Zhao, Bin, Xu, Jing, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093809/
https://www.ncbi.nlm.nih.gov/pubmed/32213463
http://dx.doi.org/10.1016/j.isci.2020.100983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093809/
https://www.ncbi.nlm.nih.gov/pubmed/32213463
http://dx.doi.org/10.1016/j.isci.2020.100983

Ejemplares similares