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Therapeutic Applications of Monoclonal Antibodies
Researchers have sought therapeutic applications for monoclonal antibodies since their development in 1975. However, murine-derived monoclonal antibodies may cause an immunogenic response in human patients, reducing their therapeutic efficacy. Chimeric and humanized antibodies have been developed th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Southern Society for Clinical Investigation. Published by Elsevier Inc.
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093874/ https://www.ncbi.nlm.nih.gov/pubmed/12120821 http://dx.doi.org/10.1097/00000441-200207000-00004 |