Therapeutic Applications of Monoclonal Antibodies

Researchers have sought therapeutic applications for monoclonal antibodies since their development in 1975. However, murine-derived monoclonal antibodies may cause an immunogenic response in human patients, reducing their therapeutic efficacy. Chimeric and humanized antibodies have been developed th...

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Detalles Bibliográficos
Autores principales: Berger, Mitchell, Shankar, Vidya, Vafai, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Southern Society for Clinical Investigation. Published by Elsevier Inc. 2002
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093874/
https://www.ncbi.nlm.nih.gov/pubmed/12120821
http://dx.doi.org/10.1097/00000441-200207000-00004

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