Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease()

Coxsackievirus B3 is the main cause of human viral myocarditis and cardiomyopathy. Virally encoded Coxsackievirus 3C protease (3C(pro)) plays an essential role in viral proliferation. Here, benserazide was discovered as a novel inhibitor from a drug library screen targeting Coxsackievirus 3C(pro) us...

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Detalles Bibliográficos
Autores principales: Kim, Bo-Kyoung, Cho, Joong-Heui, Jeong, Pyeonghwa, Lee, Youngjin, Lim, Jia Jia, Park, Kyoung Ryoung, Eom, Soo Hyun, Kim, Yong-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of European Biochemical Societies. Published by Elsevier B.V. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094222/
https://www.ncbi.nlm.nih.gov/pubmed/26022398
http://dx.doi.org/10.1016/j.febslet.2015.05.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094222/
https://www.ncbi.nlm.nih.gov/pubmed/26022398
http://dx.doi.org/10.1016/j.febslet.2015.05.027

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