Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase

Severe acute respiratory syndrome (SARS) is a respiratory disease caused by a newly found virus, called SARS coronavirus. In this study, the cleavage mechanism of the SARS coronavirus main proteinase (M(pro) or 3CL(pro)) on the octapeptide NH(2)-AVLQ ↓ SGFR-COOH was investigated using molecular mech...

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Detalles Bibliográficos
Autores principales: Du, Qishi, Wang, Shuqing, Wei, Dongqing, Sirois, Suzanne, Chou, Kuo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094278/
https://www.ncbi.nlm.nih.gov/pubmed/15691506
http://dx.doi.org/10.1016/j.ab.2004.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094278/
https://www.ncbi.nlm.nih.gov/pubmed/15691506
http://dx.doi.org/10.1016/j.ab.2004.10.003

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