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Ebola virus secreted glycoprotein decreases the anti-viral immunity of macrophages in early inflammatory responses

During Ebola virus (EBOV) infection, secreted glycoprotein (sGP) is found in large quantities in the serum of both patients and infected animal models. It is thought to serve as a decoy for anti-EBOV antibodies. Using an in vitro model incorporating treatment of non-infected human THP-1 macrophages...

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Detalles Bibliográficos
Autores principales: Bradley, Jillian H., Harrison, Ametria, Corey, Ashley, Gentry, Nathan, Gregg, Randal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094302/
https://www.ncbi.nlm.nih.gov/pubmed/29195741
http://dx.doi.org/10.1016/j.cellimm.2017.11.009